SIGA Technologies Inc.

SIGA TECHNOLOGIES TO PRESENT AT THE RODMAN AND RENSHAW ANNUAL GLOBAL INVESTMENT CONFERENCE

Thursday 06 November 2008

New York, New York, November 6, 2008 – SIGA Technologies, Inc. (NASDAQ: SIGA), a

company specializing in the development of pharmaceutical agents to fight biowarfare pathogens,

today announced that the Company’s CEO, Dr. Eric A. Rose, will be presenting at the Rodman

and Renshaw Annual Global Investment Conference, on Tuesday, November 11, 2008 at 9:30

a.m. ET at The New York Palace Hotel in New York City.

Dr. Rose will give a 20-minute presentation regarding SIGA Technologies' market positioning,

financial performance, and strategic direction, followed by a 5-minute question and answer

session. The conference is hosting a live webcast of Dr. Rose’s presentation. To access the live

webcast off the event, visit the Investor Relations section of the Company’s website,

www.siga.com, under ‘Events & Presentations’. A replay of the event will be available for 90

days following the presentation.

About SIGA Technologies, Inc.

SIGA Technologies is applying viral and bacterial genomics and sophisticated computational

modeling in the design and development of novel products for the prevention and treatment of

serious infectious diseases, with an emphasis on products for biological warfare defense. SIGA

believes that it is a leader in the development of pharmaceutical agents to fight potential biowarfare

pathogens. SIGA has antiviral programs targeting smallpox and other Category A

pathogens, including arenaviruses (Lassa fever, Junin, Machupo, Guanarito, Sabia, and

lymphocytic choriomeningitis), dengue virus, and the filoviruses (Ebola and Marburg). For more

information about SIGA, please visit SIGA’s Web site at

Contact:

KCSA Strategic Communications

Todd Fromer / Marybeth Csaby / David Burke

212-896-1215 / 1236 / 1258

Tfromer@kcsa.com / mcsaby@kcsa.com / dburke@kcsa.com

http://www.siga.com/.